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Updated: Jun 25, 2025

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
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Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

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SAGA复合体的KAT模块维持了MYCN增强神经母细胞瘤中致癌基因表达程序

Clare F Malone1,2,3, Nathaniel W Mabe1,2,3, Alexandra B Forman1,2

  • 1Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Science advances
|May 31, 2024
PubMed
概括

研究人员发现,Spt-Ada-Gcn5-乙转移酶 (SAGA) 复合体对MYCN增强神经母细胞瘤至关重要. 抑制SAGA复合体的作用

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