相关实验视频

Updated: Jun 25, 2025

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

一个全面的协议,以3特斯拉的速度对大脑进行定量磁共振成像

Dvir Radunsky¹, Chen Solomon¹, Neta Stern¹

¹Department of Biomedical Engineering, Tel-Aviv University, Tel Aviv, Israel.

|May 31, 2024

概括

一个新的定量MRI (qMRI) 协议在不到50分钟内提供全面的大脑成像. 这种快速,多参数的方法确保可重现的结果,用于先进的组织病理学分析.

科学领域:

医疗成像医学成像
神经成像是一种神经成像.
生物物理学的生物物理.

背景情况:

定量MRI (qMRI) 提供了对大脑和身体组织有价值的临床见解.
快速,准确和可重复的QMRI技术的进步使得多参数数据的获取能够用于详细的病理学评估.

研究的目的:

引入一种针对3特斯拉大脑成像优化的新型多参数qMRI协议.
为生成定量地图提供完整的后处理管道.
提供实际指导并讨论协议实施的局限性.

主要方法:

开发并验证了一种具有八个脉冲序列的多参数qMRI协议.
总扫描时间优化至50分钟以下.
包括T1,T2,T2*的生成,磁性易感性,组织分数,扩散指标和磁化转移参数.

主要成果:

协议适用于28名健康志愿者,产生与先前研究一致的定量值.
与ROI内部变异性相比,已证明人际变异性较低.
高扫描-重新扫描稳定性和可重现性在区域和受试者之间得到证实,具有强大的半球相关性 (r>0.89).

结论:

提出的qMRI协议是快速的,可重复的,并为脑成像提供全面的多参数数据.
公共可用的数据和脚本有助于纵向和多中心研究.
整合多个定量指标可以提高超出单对比成像的生物解释性.

更多相关视频

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

Published on: May 12, 2019

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...