盆地底生物力学模型的有限元分析,以阐明改善老年人排尿和排便功能障碍的机制:模型开发和验证研究协议
Rui Wang1, Guangtian Liu2, Liwei Jing1
1School of Nursing, Capital Medical University, Beijing, China.
JMIR research protocols
|May 31, 2024
概括
这项研究使用有限元建模来分析老年人的骨盆底变化,旨在通过康复了解和改善尿路和肠道功能障碍.
科学领域:
- 老年学是一门学科.
- 生物力学 生物力学
- 医疗成像医学成像
背景情况:
- 人口老龄化经历生理变化导致功能衰退,特别是尿路和肠道功能障碍.
- 由于衰老而导致的骨盆底组织学变化以及改善肠道控制的机制尚未完全理解.
研究的目的:
- 利用有限元法 (FEM) 研究康复期间盆腔内的机械特性和生理变化.
- 为了解和改善老年人泌尿和排便功能障碍提供理论支持.
主要方法:
- 使用老年男性和女性志愿者的MRI和CT数据构建了盆腔的3D有限元素模型.
- 模拟生理状态,如瓦尔萨尔瓦机动和肠道运动,以验证模型.
- 研究神经肌肉变化的影响,并量化盆底,核心肌肉和神经的贡献.
主要成果:
- 这项研究已注册在中国临床试验登记处,并收集了初始成像数据.
- 计划在2024年7月之前完成有限元模型的构建和分析.
- 研究结果预计将于2025年10月公布.
结论:
- 将开发老年人骨盆床的有限元模型,以阐明肌肉群和肠道控制之间的关系.
- 这项研究将为改善老年人泌尿和排便功能障碍的康复机制提供理论见解.
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