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Updated: Jun 25, 2025

Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages
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在XIAP缺乏症中,因特乐金-1介导的高炎症与缺陷的自有关

Dilan Dissanayake1,2,3, Ashkan Firouzabady1, Mohammad Massumi1

  • 1Cell Biology Program, SickKids Research Institute, Toronto, ON, Canada.

Blood
|May 31, 2024
PubMed
概括

与X相关的亡蛋白抑制剂 (XIAP) 缺乏导致复发性血细胞性淋巴细胞瘤 (HLH). 在特定条件下,XIAP缺乏的细胞过度产生IL-1β,这表明IL-1β阻断是一种可行的治疗方法.

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