中创伤后应激障碍:对当前证据的元分析
Chiara Pepi1, Mattia Mercier1, Licia Salimbene1
1Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies, EpiCARE, Rome, Italy.
Epilepsy & behavior : E&B
|May 31, 2024
概括
患有的人有18%的创伤后应激障碍 (PTSD) 患病率,与普通人群相比,风险增加了三倍. 早期识别和治疗PTSD对于改善患者护理至关重要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 带来了重大挑战,包括残疾,耻辱和死亡率.
- 精神病相关疾病,如情绪,焦虑和精神疾病,影响20-30%的患者.
- 创伤和童年逆境是精神病理学的危险因素,但创伤后应激障碍 (PTSD) 和之间的联系尚未得到充分研究.
研究的目的:
- 通过元分析来确定患者中PTSD的最新流行率.
- 将患者的PTSD患病率与普通人群进行比较,并探索相关因素.
主要方法:
- 进行了元分析,包括15项研究,共996名患者.
- 流行数据被汇总,并根据研究对照,发作类型和人口统计因素进行分组分析.
主要成果:
- 在患者中,PTSD的整体综合患病率为18%.
- 与普通人群相比,患者患PTSD的风险增加了三倍.
- 在不受控制的研究中 (25%) 与受控研究 (14%),以及与患者相比,在患有心理非发作 (PNES) 的患者中观察到更高的PTSD患病率.
结论:
- 创伤后应激障碍是中显著的并发症,可能与发作创伤和耻辱联系在一起.
- 改善PTSD的识别和管理是治疗途径的重要组成部分.
- 需要进一步的研究来了解和解决中PTSD患病率.
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