跨数字类型的抗真菌子用于预防和治疗 tinea pedis
Lin Du1, Lin Liu2, Shuaijun Zou1
1Department of Dermatology and Marine Biological Injuries, Naval Medical Centre, Naval Medical University, Shanghai 200052, China.
Journal of infection and public health
|May 31, 2024
概括
设计用于数字间空间的抗真菌子在预防和治疗运动员脚部 (tinea pedis) 中显示出有希望的结果. 这些子为管理这种常见的真菌感染提供了一种新的方法,特别是随着抗真菌耐药性的增加.
科学领域:
- 皮肤病学 皮肤病学
- 菌类学 菌类学是指菌类学.
- 织科学 织科学
背景情况:
- 手指间的脚是一种常见的脚部感染.
- 增加抗真菌耐药性需要替代治疗方法.
- 抗真菌子是一个潜在的日常管理解决方案.
研究的目的:
- 开发和评价的抗真菌卫生子为数字之间的 tinea pedis.
- 为了评估子的体外抗真菌活性.
- 为了确定子的预防和治疗疗效 in vivo.
主要方法:
- 抗真菌纤维被用来制造数字间子,将第三个和第四个脚分开.
- 在实验室中测试了抗真菌活性.
- 在健康个体中评估了预防效果.
- 在 tinea pedis 患者中,使用总症状得分 (TTS) 评估治疗效果.
主要成果:
- 数字间的子在体外表现出显著的抗真菌活性.
- 在体内研究显示,与普通子相比,对 tinea pedis 有显著的预防作用.
- 数字间导致患者的总症状得分 (TTS) 较低.
- 在患有 tinea pedis 的患者中观察到 72.9% 的整体疗效率.
结论:
- 数字间抗真菌子在体外具有抗真菌特性.
- 这些子提供了显著的预防性益处,可以预防指际脚.
- 这些子还在管理现有的 tinea pedis 感染方面表现出显著的治疗效果.
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