饮用水中的雌激素化合物:系统审查和风险分析
Deisi N de Souza1, Ann H Mounteer2, Gemima S Arcanjo1
1Programa de Pós-Graduação em Meio Ambiente, Águas e Saneamento, Departamento de Engenharia Ambiental, Universidade Federal da Bahia, 40210-630, Salvador, BA, Brazil.
Chemosphere
|May 31, 2024
概括
饮用水中的DEHP等雌激素化合物对健康构成高非致癌风险. 虽然雌激素活性风险较低,但潜在的相互作用需要改进的水处理技术来清除微污染物.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 雌激素化合物是模仿17β-雌激醇的内分泌干扰物,对生殖健康构成风险.
- 它们在饮用水中的存在引起了人们对人类暴露和健康影响的担忧.
- 评估这些风险需要了解化合物度及其影响.
研究的目的:
- 系统地审查饮用水中雌激素化合物的全球研究.
- 根据报告的度来估计人类健康和雌激素活性风险.
- 确定饮用水中的关键雌激素化合物及其来源.
主要方法:
- 对Web of Science,SCOPUS和PubMed数据库的系统文献审查.
- 从最初的505.5中分析了45篇选定的论文.
- 饮用水中的16种雌激素化合物的识别和量化.
主要成果:
- 确定了16种雌激素化合物,包括激素,药品和可塑剂.
- 在最高度 (1.43 mg/L) 中发现了二--2-乙烯基) 甲酸盐 (DEHP).
- 对于17α-乙烯 Estradiol和DEHP,高的非致癌风险被发现;对于 dibutyl phthalate,中等风险;对于 bisphenol A,低风险.
结论:
- 饮用水含有各种雌激素化合物,具有不同的健康风险.
- DEHP具有较低的雌激素活性风险,而其他风险可以忽略不计.
- 改善饮用水处理对于去除微污染物和减轻风险至关重要.
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