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Updated: Jun 25, 2025

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells

Published on: September 23, 2021

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通过ICAM1,EVs和瘤细胞之间的粘附促进了EV封装的多克索鲁比辛通过ICAM1传递

Shibo Wang1, Chenxiao Qiao2, Xianghui Kong2

  • 1Institute of Immunology and Department of Orthopaedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Institute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou 310006, China.

Pharmacological research
|May 31, 2024
PubMed
概括

细胞外囊泡 (EVs) 通过允许直接进入细胞质,提高疗效和降低心脏毒性来增强抗瘤药物多克索鲁比 (Dox) 的输送. 电动汽车使用独特的"接吻和运行"机制,提高了Dox进口效率.

关键词:
德克索鲁比辛是一种多克索鲁比辛.细胞外囊泡中的细胞外囊泡.在 ICAM1 中,在IFN-γγ中.这就是TNF-α.

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