在PDCoV感染期间,与IFITM3蛋白相关联的新型相互作用蛋白通过协同亲和性净化和质谱学识别出了与IFITM3蛋白相关的新型相互作用蛋白

Cheng Li1, Xiao-Ran Guo1, Zhi-Min Dong1

  • 1Tianjin Key Laboratory of Animal Molecular Breeding and Biotechnology, Institute of Animal Science and Veterinary, Tianjin Academy of Agricultural Sciences, Tianjin 300381, China; Tianjin Observation and Experimental Site of National Animal Health, Tianjin 300381, China; National Data Center of Animal Health, Tianjin 300381, China.

概括

干扰素诱导的跨膜3 (IFITM3) 蛋白活性由IFN-α增强,减少猪三角冠状病毒 (PDCoV) 感染. IFITM3与Rab9a相互作用,在PDCoV感染期间扩大其已知的细胞作用.

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