Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Group 8 metallocenes as single-source precursors for the synthesis of light-element-stabilized FCC phases under extreme conditions.

Science and technology of advanced materials·2026
Same author

High-Pressure Synthesis of a Silicon-Rich Ruthenium Silicide, RuSi<sub>3</sub>, with a 9-Coordinated Ru Site and a Si-Si Dumbbell.

Inorganic chemistry·2026
Same author

A Translational Neural Network Mechanism of Resilience: Top-Down Control and Plasticity of the Visual Cortex Relates to Resilient Outcome and Performance.

Research (Washington, D.C.)·2026
Same author

[A case of autoantibody-negative autoimmune encephalitis associated with mature ovarian teratoma, successfully treated with early ovariectomy].

Rinsho shinkeigaku = Clinical neurology·2026
Same author

An R83W mutation in Rab3A causes autosomal-dominant cerebellar ataxia.

Human molecular genetics·2026
Same author

Effective Radiotherapy for Bilateral Hip Flexion Dysfunction Due to Vertebral Metastasis at the Origin of the Psoas Major: A Case Report.

Cureus·2025

相关实验视频

Updated: Jun 25, 2025

Transcriptome Analysis of Single Cells
07:27

Transcriptome Analysis of Single Cells

Published on: April 25, 2011

29.9K

在单个神经元水平上整合生理和转录组分析.

Haruya Yagishita1, Takuya Sasaki1

  • 1Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aramaki-Aoba, Aoba-Ku, Sendai 980-8578, Japan.

Neuroscience research
|May 31, 2024
PubMed
概括

研究人员正在使用新的生理和转录基因方法将神经元活动模式与其分子构成联系起来. 这种方法有助于理解从基因到行为的神经元功能.

科学领域:

  • 神经科学是一个神经科学.
  • 分子生物学分子生物学
  • 系统神经科学 系统神经科学

背景情况:

  • 神经元表现出不同的发射模式,这对不同的大脑功能至关重要.
  • 一个重大挑战在于将这些生理尖峰模式与潜在的分子特征联系起来.

研究的目的:

  • 审查综合生理学和转录基因技术的最新研究.
  • 探索神经元活动模式和基因表达特征之间的关系.

主要方法:

  • 在体内记录和/或标记神经元活动.
  • 脑组织切片,单细胞采集和转录组分析.
  • 鉴定与记录活动模式相关的基因表达特征.

主要成果:

  • 成功识别了个别大脑神经元的基因表达特征.
  • 分子特征与活动物中特定的神经元活动模式的相关性.
  • 证明这些综合技术在不同大脑区域的适用性.

结论:

  • 整合生理和转录基因数据为理解神经元功能提供了一个强大的方法.
  • 这种方法提升了神经元的研究,从分子层面到电路和行为.
关键词:
电力生理学 电力生理学图像成像是一种成像.在RNA-seqqq.空间转录组空间转录组斯派克斯派克斯派克斯就是一个尖刺.

更多相关视频

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

4.7K
Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons
09:11

Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons

Published on: January 13, 2014

9.1K

相关实验视频

Last Updated: Jun 25, 2025

Transcriptome Analysis of Single Cells
07:27

Transcriptome Analysis of Single Cells

Published on: April 25, 2011

29.9K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

4.7K
Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons
09:11

Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons

Published on: January 13, 2014

9.1K
  • 持续的研究将加深我们对神经元活动和分子身份之间的联系的理解.