额外纤维细胞去矿化:是还是不是?
Qingli Zhou1, Yuzhu Li1, Ting Xiao2
1Department of Stomatology, The First Affiliated Hospital of Anhui Medical University, 218 Jixilu Rd., Hefei 230032, China; Key Lab. of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
概括
外纤维脱矿化不是树脂-牙结合的可靠策略. 完整的去矿化需要足够的相互作用时间,而化剂不能确保在短时间接触时可靠的结合.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料科学 牙科材料科学
- 粘附科学 粘附科学 粘附科学
背景情况:
- 树脂 - 丁粘合的耐用性对于牙科修复至关重要.
- 建议进行外纤维化去矿化,以增强结合接口.
- 额外纤维细胞去矿化的理论基础与氧酸盐溶解平衡相矛盾.
研究的目的:
- 用化剂研究牙的去矿化机制.
- 为了评估由化剂对牙脱矿化对树脂-牙粘附的影响.
- 探索额外纤维细胞去矿化作为一种结合策略的可行性.
主要方法:
- 用不同分子量 (PAAN450k,PAAN3k) 的EDTA和聚烯酸 (PAAN) 接种的已制备的聚乙烯胺作为牙修饰剂.
- 使用SEM,TEM,XPS,AFM和氧量化进行评估的脱矿化.
- 在湿和干的条件下使用微拉伸强度测试 (μTBS) 和故障模式分析评估树脂-丁丁结合.
主要成果:
- 即使没有PAAN450k和牙粉之间的直接接触,也观察到去矿化.
- 外纤维细胞去矿化不能被任何化剂诱导,无论分子量如何.
- 完全脱矿化 (外纤维和内纤维) 发生在足够的相互作用时间.
- 化剂在短的相互作用时间下没有提供可靠的牙结合.
结论:
- 外纤维脱矿化在理论上和实践中对于树脂-牙结合是不可靠的.
- 这些发现需要探索改善粘合耐久性的替代策略.
- 登丁脱矿化需要仔细考虑相互作用时间和化剂特性.
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