大麻食用品对驾驶和血液THCTHC的影响
S Zhao1,2, B Brands1,2,3, P Kaduri4,5,6
1Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.
Journal of cannabis research
|June 1, 2024
概括
大麻食用品可能会令人陶醉,并影响驾驶性能,尽管损害可能很难检测到. 饮酒后2小时,驾驶速度下降,但血液THC水平与驾驶变化无关.
科学领域:
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
- 法医科学 法医科学 法医科学
背景情况:
- 大麻使用会影响驾驶能力,主要是由于delta-9-tetrahydrocannabinol (THC).
- 现有的驾驶障碍法规通常依赖于吸烟大麻的数据.
- 大麻食用品对驾驶和血液THC水平的影响仍未得到充分研究.
研究的目的:
- 为了研究食用大麻食用品对模拟驾驶性能的影响.
- 为了评估血液THC水平和食用大麻消费后的主观经验.
- 为了确定驾驶障碍是否可检测,并与食用后的THC水平相关.
主要方法:
- 参与者在消费他们喜欢的大麻食用品之前和之后驾驶模拟器.
- 控制组没有使用大麻 (THC或CBD).
- 血液样本被分析到THC,代谢物和CBD;主观经验也被记录下来.
主要成果:
- 大麻食用品导致消费后2小时的平均驾驶速度下降,但不是在以后的时间点.
- 没有观察到侧向位置,最大速度,速度变化或反应时间的显著变化.
- 血液THC水平上升,但仍然很低 (大约1%) 2.8 ng/mL在2小时) 并与驾驶障碍无关.
- 主观评估表明酒精中毒和减少驾驶意愿长达7小时.
结论:
- 这项研究是首次研究大麻食用品对模拟驾驶的影响.
- 大麻食用品导致中毒,主观报告证明了这一点.
- 在食用大麻后检测驾驶障碍可能是具有挑战性的,因为各种影响和低血THC水平.
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