厌氧血培养在新生儿败血症评估中的实用性
Amanda Gottschalk1, Sarah Coggins1,2,3, Miren B Dhudasia2,3
1Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Journal of the Pediatric Infectious Diseases Society
|June 1, 2024
概括
将无氧血培养瓶添加到新生儿败血症评估中,有助于识别有氧瓶遗漏的病原体,并加快病原体检测. 这提高了新生儿重症监护室 (NICU) 的诊断准确度.
科学领域:
- 新生儿重症监护室 (NICU) 医学 新生儿重症监护室 (NICU) 医学
- 临床微生物学 临床微生物学
- 传染性疾病 传染性疾病
背景情况:
- 临床医生在使用无氧血培养来评估新生儿败血症方面存在差异.
- 无氧血培养瓶在NICU的临床实用性仍在争论中.
研究的目的:
- 为了确定厌氧血培养瓶是否在新生儿败血症评估中提供临床相关信息.
- 评估厌氧瓶是否能恢复有氧瓶遗漏的病原体,或提供更快的检测.
主要方法:
- 从NICU婴儿血液培养的回顾性队列研究 (2015年8月至2023年8月).
- 同时获得的有氧和无氧培养瓶之间的病原体恢复和阳性时间的比较.
- 分析了182个有氧-无氧对,具有阳性病原体恢复.
主要成果:
- 在17.6%的病例中,无氧瓶只恢复了病原体 (32/182).
- 像凝聚酶阴性葡萄球菌这样的选择性无气体通常被恢复.
- 无氧瓶在67.3%的配对阳性培养物中显示出较早的病原体检测 (较短的阳性时间).
结论:
- 无氧血培养瓶可以提高新生儿败血症评估中的病原体检测.
- 它们的纳入可以导致更早地识别致病原体,改善患者管理.
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