COVID-19疫苗接种与气味和味道的变化相关联
Tyler J Gallagher1, Miti Parikh1, Kevin Herrera1
1Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
概括
与流感,TDAP和肺炎球菌疫苗相比,COVID-19疫苗与气味和味道变化率较低有关. 这一发现支持严重急性呼吸系统综合征冠状病毒2疫苗接种的整体安全性.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 对于严重急性呼吸系统综合征冠状病毒2 (COVID-19) 的疫苗犹是令人担忧的,部分原因是对副作用的担忧.
- 了解疫苗接种后感官障碍的比较发病率对于公众的信任和疫苗接种至关重要.
研究的目的:
- 为了比较COVID-19疫苗接种后嗅觉和味觉障碍的发生率与其他常见疫苗的发生率.
- 为了调查COVID-19疫苗关于感官副作用的安全性.
主要方法:
- 一项使用TrinetX数据库的回顾性队列研究.
- 包括那些在2020年12月至2023年8月期间接种了COVID-19 (第一系列或增剂),流感,结节炎,白喉,百日咳 (TDAP) 或肺炎球菌疫苗的人.
- 使用1:1的倾向分数匹配来比较结果.
主要成果:
- 与流感,TDAP和肺炎球菌疫苗相比,在COVID-19第一系列和强剂疫苗后,嗅觉和味觉障碍的可能性显著降低.
- 具体的几率比率 (OR) 表明,在整个比较中,COVID-19疫苗的风险要低得多.
结论:
- 该研究提供了证据表明,与其他常用疫苗相比,COVID-19疫苗接种与嗅觉和味觉障碍的风险较低有关.
- 这些发现有助于支持COVID-19疫苗安全性的证据,并可能有助于解决疫苗犹.
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