间歇性肺病作为炎症性肠病患者死亡率的新兴贡献者:基于人口的流行病学研究
Atefeh Vaezi1, Tracy Ashby1, Michael Schweitzer1
1Division of Pulmonary, Critical Care, and Sleep Medicine, College of Medicine-Jacksonville, University of Florida, Jacksonville, Florida, USA.
Clinical and translational gastroenterology
|June 1, 2024
概括
在炎症性肠病 (IBD) 患者中,间歇性肺病 (ILD) 的死亡率正在增加. 在IBD患者的早期ILD查对于更好的管理和结果至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 炎症性肠病 (IBD) 包括克罗恩病和性结肠炎.
- 间歇性肺病 (ILD) 是IBD的一个已知的并发症.
- ILD对IBD死亡率的影响需要进一步调查.
研究的目的:
- 调查ILD对IBD诊断患者死亡率的贡献.
- 分析20多年来IBD患者与ILD相关死亡的趋势.
主要方法:
- 从2001年到2020年,在美国进行了一项以人口为基础的回顾性流行病学研究.
- 数据来源于流行病学研究的广泛在线数据数据库.
- 用国际疾病分类,第十次修订代码分析了死亡率数据,根据人口统计学分层的年龄调整死亡率 (AMR).
主要成果:
- 从2001年到2020年,IBD患者中有57,967人死亡,AMR显著增加.
- ILD导致1.19%的IBD死亡,显示出死亡率的上升趋势.
- 在克罗恩氏病死亡人数中,ILD更为普遍,并且在性别和白人人口中呈现上升趋势.
结论:
- 在IBD患者中观察到与ILD相关的死亡率有所增加.
- 在IBD人群中,有必要进行系统的ILD查.
- 在IBD患者中,早期发现和治疗ILD至关重要.
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