儿童的圆形孔:对最近进展的回顾
Tingting Zhang1, Chao Gao1, Wei Chen1
1Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Changle West Road, Xi'an, 710032, China.
Pediatric cardiology
|June 1, 2024
概括
儿童的卵孔 (PFO) 需要仔细考虑,因为它可能与中风和其他疾病有关. 对于孤立的PFO,治疗通常是不必要的,但对于复杂的病例,建议进行咨询.
科学领域:
- 心脏病学 心脏病学
- 儿科神经学 儿科神经学
- 医疗成像医学成像
背景情况:
- 对于专利卵孔 (PFO) 的管理指南对于成年人来说已经存在,但最佳的儿科PFO治疗仍然不清楚.
- PFO与儿童的各种临床综合征和潜在并发症有关,包括密码性中风和悖论性栓塞.
研究的目的:
- 综合分析临床综合征,成像诊断和儿科患者PFO的管理.
- 审查目前关于PFO与特定儿科疾病之间关联的证据.
- 为儿童PFO的诊断和治疗方法提供指导.
主要方法:
- 在主要的电子数据库 (PubMed,Cochrane,Web of Science,EMBASE) 进行了全面的文献搜索,截至2024年2月1日.
- 从最初的583篇文章中,选出了54篇相关文章进行深入审查.
- 系统评估了有关PFO在儿科中风,偏头痛,状细胞疾病和罕见综合征中的作用的证据.
主要成果:
- 通过PFO的右向左分线与儿童的密码性中风有关,尽管它与偏头痛与光环的联系缺乏强有力的证据.
- 患有状细胞疾病和PFO的儿童面临悖论性栓塞的风险增加;罕见的综合征,如平nea-orthodeoxia综合征,心肌梗塞和减压疾病可能发生.
- 推用于儿科PFO诊断的对比性胸前心电回声学,因为它的有效性和避免麻醉.
结论:
- 在儿童中孤立的PFO通常不需要额外的治疗,因为缺乏证据表明未来的并发症.
- 对于在特殊情况下患有PFO的儿童,在考虑医疗干预之前,定制的跨学科咨询是至关重要的.
- 可能需要进一步的研究来澄清长期影响和儿童群体中PFO的最佳管理策略.
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