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非传统的T细胞影响异构血型细胞移植后临床结果

Lama Siblany1,2, Nicolas Stocker1,2, Laure Ricard1,2

  • 1INSERM, Centre de Recherche Saint-Antoine (CRSA), Sorbonne Université, F-75012, Paris, France.

Journal of clinical immunology
|June 1, 2024
PubMed
概括

在全基造血细胞移植 (allo-HCT) 后,粘膜相关的不变T细胞 (MAIT) 和特定的玛-三角形 (γδ) T细胞子集的早期恢复显著改善了患者的生存率,并减少了GvHD. MAIT细胞频率和Vδ2+T细胞上的CD26表达是成功的alo-HCT结果的关键指标.

关键词:
剧烈的移植与宿主疾病.全基性造血细胞移植 (allo-HCT) 是一种全基性细胞移植.粘膜相关的不变T细胞 (MAIT)在Vδ2+ T细胞中.

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