在极度或非常早产的新生儿中,在立即产后过渡期间,对动脉氧和,心率和大脑氧和的参考范围
Christina H Wolfsberger1, Bernhard Schwaberger1, Berndt Urlesberger1
1Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria; Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
The Journal of pediatrics
|June 1, 2024
概括
对于极度早产新生儿,为动脉氧和 (SpO2),心率 (HR) 和脑氧和 (crSO2) 定义了新的百分位图表,结果有利. 这些图表有助于在出生后的关键过渡期优化氧化.
科学领域:
- 新生儿生理学 新生儿生理学
- 儿科重症监护 儿科重症监护 儿科重症监护
- 医疗器械技术 医疗器械技术
背景情况:
- 确定早产新生儿生理参数的参考范围对于临床管理至关重要.
- 目前关于极度早产婴儿在出生后立即过渡期间的动脉氧和 (SpO2),心率 (HR) 和大脑氧和 (crSO2) 的数据有限.
- 在这个脆弱人群中优化氧化和血液动力学可以影响神经发育结果.
研究的目的:
- 在出生后的第一个15分钟内定义SpO2,HR和crSO2的规范百分位图表.
- 提供非常或极度早产新生儿的参考数据,并提供有利的结果.
- 在早产婴儿稳定期间支持临床决策.
主要方法:
- 来自COSGOD III试验的数据的二次分析.
- 包括早产的新生儿,可见脑氧度测量结果和有利的结果 (没有脑损伤的生存).
- 排除患有早期炎症性疾病的婴儿. 使用脉冲氧计,心电图/脉冲氧计和近红外光谱分别测量了spO2,HR和crSO2.
主要成果:
- 总共分析了207名早产新生儿 (妊娠年龄为29.7周).
- 在出生后的前15分钟,每分钟定义了SpO2,HR和crSO2的第10至第90百分位图表.
- 为SpO2 (例如2分钟时32%),HR (例如2分钟时70bpm) 和crSO2 (例如2分钟时15%) 提供了特定的第10百分位数值.
结论:
- 这项研究在非常/极度早产新生儿中为SpO2,HR和crSO2提供了新的百分位图表,结果有利.
- 这些图表可以帮助临床医生准确地定位氧化和指导干预措施在立即产后稳定期.
- 实施可能会改善在关键的产后过渡期间的氧化管理.
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