潜在的微血栓形成风险及其管理在加热盐水增强的射频针尖导管切除过程中
Atsushi Suzuki1, H Immo Lehmann2, Hiroki Konishi3
1Translational Interventional Electrophysiology Laboratory, Mayo Clinic/St. Marys Campus, Rochester, Minnesota; Department of Cardiology, Yodogawa Christian Hospital, Osaka, Japan.
Heart rhythm
|June 1, 2024
概括
在左心室 (LV) 中用盐水增强的射频 (SERF) 切除会造成大病变,而不会增加栓塞事件. 这证明了SERF的剥离.
科学领域:
- 心血管干预 心血管干预
- 电力生理学 电力生理学
- 医疗器械技术 医疗器械技术
背景情况:
- 在左心室 (LV) 中用盐水增强的射频 (SERF) 切除的栓塞风险还不清楚.
- 调查潜在的栓塞事件对于心脏剥离手术期间的患者安全至关重要.
研究的目的:
- 在LV中SERF切除过程中评估微栓塞的形成.
- 为了比较SERF切除与标准灌尖端射频 (S-RF) 切除关于栓塞事件和病变大小.
主要方法:
- 在使用SERF和S-RF导管的猪身上进行了射频除程序.
- 微泡形成的评估是使用心内心声谱进行的.
- 监测了微泡,微栓塞信号和微粒,并对栓塞事件进行了组织学分析.
主要成果:
- 在SERF和S-RF (30W) 组之间没有观察到微泡体积或微血栓信号的显著差异.
- 与S-RF 30W和50W相比,SERF剥离产生了明显更大的病变.
- 组织学检查显示,大脑或其他器官中没有栓塞事件.
结论:
- 通过SERF切除,可以安全地创建大量的左心室病变.
- 通过 SERF 除的疗效和安全性得到了支持,因为没有增加的栓塞事件.
- 一级微气泡与有效和安全的SERF剥离结果相关.
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