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基于生物宏分子的被动透增强技术在表面瘤治疗中的应用:一篇综述

Weiqiang Han1, Fengyu Liu2, Mehdi Muhammad1

  • 1Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, China.

International journal of biological macromolecules
|June 1, 2024
PubMed
概括

基于生物宏分子的被动透增强技术 (PPET) 为表面瘤治疗提供了一个有希望的,非侵入性的方法. 这些技术利用生物相容的纳米载体来改善通过皮肤递送药物,并实现有针对性的,可控的药物释放.

关键词:
生物巨分子分子纳米载体纳米载体是什么被动透增强技术是一种被动透增强技术.表面瘤治疗方法 表面瘤治疗方法通过皮肤传递药物.

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After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...