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Updated: Jun 24, 2025

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation

Published on: June 21, 2016

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在胚胎发育过程中,IκBα通过视网酸控制了造血干细胞的休眠状态

Roshana Thambyrajah1,2, Maria Maqueda3,4,5, Muhammad Zaki Fadlullah6

  • 1Program in Cancer Research, Hospital del Mar Research Institute, Barcelona, Spain. roshanathambyrajah@gmail.com.

Nature communications
|June 1, 2024
PubMed
概括

IκBα通过平衡视网膜酸信号和PRC2活动来调节造血干细胞 (HSC) 增殖. 失去IκBα会损害HSC的增殖,改变基因表达,影响它们的发育潜力.

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Analysis of Retinoic Acid-induced Neural Differentiation of Mouse Embryonic Stem Cells in Two and Three-dimensional Embryoid Bodies09:04

Analysis of Retinoic Acid-induced Neural Differentiation of Mouse Embryonic Stem Cells in Two and Three-dimensional Embryoid Bodies

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Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation11:40

Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation

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