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相关概念视频

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

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When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
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¹³C NMR: ¹H–¹³C Decoupling01:04

¹³C NMR: ¹H–¹³C Decoupling

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The probability of having two carbon-13 atoms next to each other is negligible because of the low natural abundance of carbon-13. Consequently, peak splitting due to carbon-carbon spin-spin coupling is not observed in spectra. However, protons up to three sigma bonds away split the carbon signal according to the n+1 rule, resulting in complicated spectra.
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
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Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
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Sub2Full:分割频谱以促进光学连贯性断层扫描除斑,而没有清洁数据.

Lingyun Wang, Jose A Sahel, Shaohua Pi

    Optics letters
    |June 2, 2024
    PubMed
    概括

    我们开发了Sub2Full (S2F),这是一种用于光学连贯性断层扫描 (OCT) 图像脱斑的新型自主监督方法. 这种技术可以提高可见光OCT (Vis-OCT) 的图像质量,而不需要清洁的参考数据.

    科学领域:

    • 生物医学光学 生物医学光学
    • 医疗成像医学成像
    • 图像处理 图像处理

    背景情况:

    • 斑点噪声在光学一致性断层扫描 (OCT) 中显著降低图像质量,特别是在高分辨率可见光OCT (vis-OCT) 中.
    • 现有的降噪方法往往需要清洁的,没有工件的数据,这对于海外国家和地区来说是很难获得的.
    • 图像质量的恶化会影响精细结构的可视化,例如视网膜中的亚层细节.

    研究的目的:

    • 引入一个创新的自我监督的学习策略,用于OCT形象脱光.
    • 为应对高分辨率视OCT成像中斑点噪声的挑战.
    • 开发一种不需要配对清洁数据进行培训的方法.

    主要方法:

    • 一个名为Sub2Full (S2F) 的新型自主监督策略被提出用于OCT脱皮.
    • 该方法使用两个重复的B扫描:通过分割第一个扫描的频谱来生成低分辨率输入.
    • 第二次扫描的全光谱作为训练的高分辨率目标.

    主要成果:

    • Sub2Full (S2F) 方法在可见光OCT (视OCT) 视网膜图像上成功验证.
    • 该技术证明了有效的脱落,改善了视网膜外侧亚层结构的可视化.
    • 在性能方面,S2F优于已有的自我监督方法,如Noise2Noise (N2N) 和Noise2Void (N2V).

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    Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
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    结论:

    • 拟议的Sub2Full (S2F) 战略为没有清洁数据的OCT图像脱光提供了有效的解决方案.
    • 这种自我监督的方法显著提高了对OCT的图像质量,有助于可视化微妙的视网膜结构.
    • S2F代表了用于OCT应用的医疗图像处理的有希望的进步.