针对慢性疾病个性化预防的生物标志物:为三个快速范围审查提供一个共同的协议
E Plans-Beriso1,2, C Babb-de-Villiers3, D Petrova4,5,6
1Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain. elena.plans@isciii.es.
Systematic reviews
|June 2, 2024
概括
本综述绘制了用于个性化预防癌症,心血管和神经退行性疾病的生物标志物的地图. 它确定了研究缺口,以指导未来的医疗保健策略和改善临床结果.
科学领域:
- 生物医学研究的研究.
- 预防医学 预防医学
- 基因组学和生物信息学
背景情况:
- 个性化预防利用个人生物,环境和行为数据进行有针对性的干预.
- PROPHET项目旨在发现当前个性化预防方法中的差距.
- 这一审查是制定欧盟战略研究和创新议程的更大倡议的一部分.
研究的目的:
- 系统地绘制和审查有关生物标志物的证据,以实现个性化预防.
- 专注于癌症,心血管和神经退行性疾病.
- 在一般和高风险人群中确定风险预测和分层的生物标志物.
主要方法:
- 同时进行三次快速范围审查 (2023年2月至6月).
- 在 Medline 和 Embase 搜索 2020-2023 年的出版物.
- 两名审稿人对10%的论文进行选;提取生物标志物的数据,用于风险预测和分层.
主要成果:
- 审查将提供相关生物标志物的证据地图.
- 结果将突出针对个性化预防的现有和正在开发的生物标志物.
- 鉴定的生物标志物将有助于根据疾病风险对个体进行分层.
结论:
- 这项研究将为制定欧盟针对个性化预防的战略研究和创新议程提供信息.
- 这些发现将有助于推进医疗保健中的个性化预防策略.
- 识别有效的生物标志物对于改善主要疾病领域的临床结果至关重要.
关键词:
生物标志物 生物标志物癌症 癌症 癌症 癌症心血管疾病的心血管疾病.慢性疾病 慢性疾病这是新质体新质体.神经退行性疾病的神经退行性疾病个性化预防 个性化预防精准医学是一门精准的医学.精确的预防方法.更多相关视频
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