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在接受机械血栓切除术的急性缺血性中风患者中,血栓组成和预后之间的关系
Xuyan Zhang1, Xinzheng Fu1, Zhouming Ren1
1Department of Neurology, Haining People's Hospital, Jiaxing, China.
概括
在急性缺血性中风患者中,富含红细胞的血栓与机械血栓切除术后更快的再输血时间和更好的临床结果相关. 血栓的组成可以指导治疗策略.
科学领域:
- 神经学 神经学
- 心血管研究研究心血管研究
- 病理学 病理学 病理学
背景情况:
- 机械血栓切除术是急性缺血性中风的主要内血管治疗方法.
- 血栓组合与治疗和成像相关研究,但其与临床结果的联系较少被探索.
研究的目的:
- 调查急性缺血性中风机械血栓切除术患者中血栓组成和临床结果之间的关联.
主要方法:
- 追溯分析50名急性缺血性中风患者的回收血栓.
- 组织病理学检查 (HE染色) 量化红细胞,白细胞,血小板和纤维素.
- 根据主要成分分类为富含红细胞和富含纤维素的组.
主要成果:
- 富含红细胞的血栓 (23名患者) 与穿刺到再输血的时间缩短有关.
- 富含红细胞和富含纤维素的组之间没有显著的人口或基线临床差异.
- 在90天的随访中,富含红细胞的血栓与较低的NIHSS和更好的功能结果相关 (mRS 0-2).
结论:
- 富含红细胞的血栓与急性缺血性中风中改善的再输血时间和有利的临床结果有关.
- 血栓的组成可以为内血管治疗的机械血栓切除策略提供信息.
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