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Updated: Jun 24, 2025

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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结合核酸对Rab3A的二次结构,热稳定性和酸化的影响

Genta Ito1, Taisuke Tomita2, Naoko Utsunomiya-Tate1

  • 1Department of Biomolecular Chemistry, Faculty of Pharmaceutical Sciences, Teikyo University, Japan.

Biochemical and biophysical research communications
|June 2, 2024
PubMed
概括

与GDP相关的Rab3A被LRRK2优先酸化,从而影响帕金森病 (PD) 的发病. 核酸结合显著影响Rab3A的热稳定性和LRRK2酸化,这对于理解PD机制至关重要.

关键词:
一个圆形的二重化.差分扫描光测量 差分扫描光测量富含白素的重复激酶2帕金森病是帕金森病的一种.酸化是指酸化的方法.拉布3A 拉布3A 拉布3A 拉布3A

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