在有物质使用和双重疾病的患者中微清除C型肝炎 - - 一项葡萄牙研究
Isabela Faria1, Rita Facão2, Filipa Murta3
1Psychiatry Department, Coimbra Hospital and University Center (CHUC), Portugal.
Japanese journal of infectious diseases
|June 2, 2024
概括
这项研究发现葡萄牙精神病患者中肝炎C病毒 (HCV) 感染的患病率较高. 早期检测和干预对于这个脆弱的人群至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- 慢性肝炎C (CHC) 是一个重要的公共卫生问题.
- 肝炎C病毒 (HCV) 感染在患有精神疾病的人群中更为普遍.
- 之前没有研究研究葡萄牙患者的HCV患病率,这些患者同时患有精神病和物质使用障碍.
研究的目的:
- 确定在科因布拉医院和大学中心 (CHUC) 双病理科治疗的患者中HCV抗体和CHC的患病率.
- 描述与此患者队列中HCV感染相关的人口和风险因素.
主要方法:
- 进行了一项观察性,前性研究.
- 来自双重病理门诊和住院病房的149名患者进行了HCV抗体测试.
- 检测到HCVRNA,以确认活动的CHC.
主要成果:
- 17.4%的患者检测出HCV抗体呈阳性.
- 7.4%的人有可检测的HCVRNA,表明CHC.
- 确认的CHC病例主要是50-59岁的男性住院患者,有多个性伴侣,有药物使用障碍病史.
结论:
- 与葡萄牙普通人口相比,患有双重精神疾病和物质使用障碍的患者中,HCV抗体和CHC的患病率显著更高.
- 这凸显了在精神病学环境中针对HCV进行有针对性的查和综合治疗的必要性.
- 调查结果强调了解决这一群体中不保护性行为和物质使用等风险因素的重要性.
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