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Updated: Jun 24, 2025

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为罕见癌症寻找最佳时代的剂量

Yonina R Murciano-Goroff1, Sean M Devlin1, Alexia Iasonos1

  • 1Memorial Sloan Kettering Cancer Center, New York, New York.

Cancer discovery
|June 3, 2024
PubMed
概括

开发新的癌症药物对于罕见的亚型是很困难的. 这项研究为小型患者组提出了剂量确定策略,与FDA Project Optimus指南保持一致.

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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