影响中枢神经系统的因素 中枢神经系统药物 抑郁症和住院老年人的行为变化
Juliessa M Pavon1,2,3,4, Audrey D Zhang4, Laura J Fish5,6
1Division of Geriatrics, Duke University, Durham, North Carolina, USA.
Journal of the American Geriatrics Society
|June 3, 2024
概括
住院治疗为老年人提供了一个关键的机会,可以减少中枢神经系统 (CNS) 药物的处方. 在住院期间改善沟通和患者参与可以增强中枢神经系统的药物治疗.
科学领域:
- 老年人药理学老年人药理学
- 质量健康研究 质量健康研究
- 药物的安全性 药物的安全性
背景情况:
- 中枢神经系统 (CNS) 药物增加了老年人的发病率和死亡率.
- 住院治疗为药物治疗提供了一个机会.
- 了解患者和临床医生的观点对于有效的抑郁症治疗干预至关重要.
研究的目的:
- 调查临床医生和患者在住院期间对压抑中枢神经系统药物的看法.
- 为了确定阻碍和促进中枢神经系统药物在住院环境下下降的障碍和促进者.
- 为优化医院处方流程提供干预措施和建议.
主要方法:
- 涉及医院医生,初级保健提供者,药剂师和60岁以上的患者的定性研究.
- 半结构面试和焦点小组被用来收集关于药物知识,抑郁症经验和决策偏好的数据.
- 能力,机会,动机和行为 (COM-B) 框架指导了影响主题的分析.
主要成果:
- 52名参与者确定了中枢神经系统药物处方步骤的促进者和障碍.
- 多学科团队和患者参与是关键的促进因素;挑战包括描述病情的时间和程度.
- 建议包括早期药剂师参与,加强患者教育,共享决策,标准化出院说明和过渡护理呼叫.
结论:
- 医院干预可能会导致中枢神经系统药物对老年人产生抑郁作用.
- 解决住院和门诊机构之间的沟通,教育和护理协调差距至关重要.
- 增强抑郁症描述过程需要专注于患者参与和多学科合作.
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