相关实验视频

Updated: Jun 24, 2025

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
09:35

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis

Published on: July 18, 2011

13.5K

对于哺乳动物耳放大器的普雷斯介导快速电动性的频率依赖性

Satoe Takahashi, Yingjie Zhou, Mary Ann Cheatham

    bioRxiv : the preprint server for biology
    |June 3, 2024
    PubMed
    概括

    与聋相关的前列素变异减少了外发细胞 (OHC) 功能,但没有消除它. 这一发现表明了通过增强OHC电动性来治疗听力损失的潜在治疗策略.

    更多相关视频

    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats09:23

    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

    Published on: May 24, 2018

    9.5K
    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea09:54

    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

    Published on: May 10, 2019

    11.8K

    相关概念视频

    The Cochlea01:13

    The Cochlea

    The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
    44.7K
    Muscle Stimulation Frequency01:22

    Muscle Stimulation Frequency

    The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
    Wave summation
    At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
    2.1K
    Hair Cells01:22

    Hair Cells

    Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
    40.2K
    Action Potential: Phases of Stimulation01:28

    Action Potential: Phases of Stimulation

    The action potential is a complex electrical event that occurs in excitable cells, such as neurons and muscle cells. It consists of several distinct phases, each with specific characteristics.
    Resting Phase:
    In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
    5.4K
    Motor Unit Stimulation01:20

    Motor Unit Stimulation

    When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
    The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
    1.5K
    Perceiving Loudness, Pitch, and Location01:21

    Perceiving Loudness, Pitch, and Location

    The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
    Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
    205