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Updated: Jun 14, 2026

Ex vivo Live Imaging of Lung Metastasis and Their Microenvironment
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Ex vivo Live Imaging of Lung Metastasis and Their Microenvironment

Published on: February 3, 2016

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一个体内"转向模型"揭示了RanBP9在肺巨细胞中的新相互作用

Yasuko Kajimura, Anna Tessari, Arturo Orlacchio

    bioRxiv : the preprint server for biology
    |June 3, 2024
    PubMed
    概括

    支架蛋白 Ran 结合蛋白 9 (RanBP9) 在巨细胞中具有未知的功能. 一种新的小鼠模型显示RanBP9与不同的蛋白质相互作用,影响免疫反应和新陈代谢.

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    Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung

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    Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo06:29

    Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo

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    相关概念视频

    Directionality of Nuclear Transport01:42

    Directionality of Nuclear Transport

    Ras-related nuclear protein or Ran is a small G protein that cycles between its GTP and GDP bound states. Ran specific regulators, a Ran GTPase Activating Protein or RanGAP present in the cytosol and a Ran guanine nucleotide exchange factor or RanGEF present inside the nucleus regulate GTP/GDP exchange. A high concentration of GTP inside the cells, in addition to this asymmetric distribution of  Ran-specific regulators, leads to a higher RanGTP concentration inside the nucleus. This...