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人类听觉皮层中自然声音的处理复杂性和时间表的层次结构
Kyle M Rupp1, Jasmine L Hect1, Emily E Harford1
1Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
bioRxiv : the preprint server for biology
|June 3, 2024
概括
人类听觉皮层通过表示复杂性和整合时间表来组织声音分类,揭示听觉感知的层次处理原则. 这项研究利用患者的深度神经网络绘制了神经对声音的反应.
科学领域:
- 神经科学是一个神经科学.
- 听觉感知是一种听觉感知.
- 计算神经科学是一种神经科学.
背景情况:
- 有效的听觉行为依赖于分类不同的声音.
- 在听觉皮层中声音分类的组织和动态仍然不完全理解.
- 之前的研究缺乏在听觉皮层中神经表示和时间处理的详细映射.
研究的目的:
- 调查听力皮层关于声音分类的功能组织.
- 将神经表征和信息整合时间尺度的复杂性映射到整个听觉皮层区域.
- 在听觉处理中探索表示复杂性和时间整合窗口之间的关系.
主要方法:
- 在20名患者中进行了脑内录音,这些患者在听自然声音时参与了录音.
- 编码模型使用来自深度神经网络 (DNN) 的特征来预测神经反应,用于声音分类.
- 通过最好预测神经活动的DNN层深度来评估表示复杂性;估计了时间整合窗口.
主要成果:
- 高精度的编码模型揭示了听觉皮层中表示复杂性的地形组织,与DNN层深度相关 (浅:核心,中间:侧带,深:带).
- 在区域内观察到表示复杂性的梯度,沿着特定的解剖轴增加 (核心/侧腰带的后中间到前侧侧;腰带的后部到前部和背部到腹部).
- 与侧带和带区域相比,在核心听觉皮层中发现了较短的信息集成窗口,集成窗口的长度和核心的处理复杂性之间存在相关性.
结论:
- 处理时间尺度和复杂性的等级,以及它们的相互作用,代表了听觉流的基本组织原则.
- 这种层次组织支持复杂的,抽象的听觉信息的感知.
- 这些发现提供了听觉皮层功能的详细地图,将解剖位置与表示内容和时间动态联系起来.
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