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Updated: Jun 24, 2025

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
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High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy

Published on: February 7, 2019

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调节转录因子DNA结合选择性的pH动态的作用

Kyle P Kisor, Diego Garrido Ruiz, Matthew P Jacobson

    bioRxiv : the preprint server for biology
    |June 3, 2024
    PubMed
    概括

    细胞内pH动态通过改变转录因子DNA结合直接调节基因表达. 在转录因子中保存的histidine作为pH传感器,影响细胞行为.

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