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Updated: Jun 24, 2025

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白血病抑制因子 (LIF) 受体放大了肺纤维化中的纤维细胞的致病激活

Hung N Nguyen, Yunju Jeong, Yunhye Kim

    bioRxiv : the preprint server for biology
    |June 3, 2024
    PubMed
    概括

    向白血病抑制因子受体 (LIFR) 为纤维性疾病提供了一个新的治疗策略. 阻断LIFR会减少纤维细胞激活和亲纤维细胞基因表达,这表明它在纤维化中扮演主放大器的角色.

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