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使用新药发现平台识别PPM1D的小分子抑制剂

Wei Jiang1,2, Subrata Shaw1,2, Jason Rush1,2

  • 1Broad Institute of MIT and Harvard University, Cambridge, MA, USA.

bioRxiv : the preprint server for biology
|June 3, 2024
PubMed
概括

研究人员发现了PPM1D的新抑制剂,PPM1D是一种与癌症有关的蛋白质. 抑制PPM1D对DNA损伤反应 (DDR) 的影响不同于其他癌症疗法,提供新的治疗策略.

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