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摄入量与喘患者肺功能之间的相关性:一个横截面研究.
Hejun Jiang1, Guijun Yang1, Jing Chen2
1Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
更高的摄入量与喘患者的肺功能改善有关. 建议每天摄入137.65微克至200微克的,以使喘患者的肺功能最佳.
科学领域:
- 营养科学 营养科学
- 肺部病理学 肺部病理学
- 环境健康 环境健康
背景情况:
- 喘是一种慢性呼吸道疾病,影响着全世界数以百万计的人.
- 肺功能障碍是喘的一个关键特征.
- 饮食因素,包括微量元素,可能会影响喘的严重程度和进展.
研究的目的:
- 研究摄入量与喘患者肺功能参数之间的关联.
- 为了确定摄入的水平是否与喘患者肺功能改善相关.
主要方法:
- 分析了来自美国国家健康和营养检查调查 (NHANES) 的4541名参与者的数据.
- 利用多变量线性回归,方差膨胀系数,受限立方线和量子回归来评估摄入量与肺功能之间的关系.
- 将摄入量分为四个四分之一 (Q1: ≤76.75 mcg/d,Q2: 76.75-105.1 mcg/d,Q3: 105.1-137.65 mcg/d,Q4: ≥137.65 mcg/d) 的类别.
主要成果:
- 喘与强迫呼吸量1秒到强迫生命能力 (FEV1/FVC) 的比率和FEV1.1的比率呈负相关性.
- 摄入量与FEV1和强迫生命能力 (FVC) 有积极关联.
- 较高的摄入量 (Q4) 与低摄入量 (Q1) 相比,在患者中显著改善了FVC和FEV1. 对FVC的积极影响取决于剂量.
结论:
- 摄入量与喘患者的肺功能之间存在正相关性,这种关联的强度取决于摄入水平.
- 对于喘患者来说,建议的每日摄入量在137.65微克至200微克之间,以提高肺功能.
- 充足的摄入量可能是管理喘患者肺功能的一个有益的策略.
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