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Updated: Jun 24, 2025
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目前的临床实践包括细胞还原性手术 (CRS) 和高热性腹腔内化疗 (HIPEC)
Miklos Acs1,2, Maximilian Babucke1, Maximilian Jusufi3
1Department of General and Visceral Surgery, Hospital Barmherzige Brüder, Regensburg, Germany.
Innovative surgical sciences
|June 3, 2024
概括
细胞还原性手术 (CRS) 和高热性腹腔内化疗 (HIPEC) 为某些患有腹腔转移的患者提供了有利的结果. 本综述总结了对原发性恶性瘤及其腹传播的CRS和HIPEC的最新发现.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 腹膜表面恶性瘤带来复杂的治疗挑战,预后不确定.
- 细胞还原性手术 (CRS) 与高热性腹膜内化学疗法 (HIPEC) 结合,对某些患有腹膜转移 (PM) 的患者显示出有前途.
研究的目的:
- 总结CRS和HIPEC对腹传播的原发性恶性瘤的现有证据.
- 提供关于CRS和HIPEC的指示,目标群体和风险因素的最新报告.
主要方法:
- 2016年至2022年间发表的研究文献综述.
- 在Medline,Embase和Google学者中进行的搜索.
- 专注于报告长期无进展生存 (PFS) 和整体生存 (OS) 数据的研究.
主要成果:
- 在精心挑选的患者中,CRS和HIPEC与有利的长期结果有关.
- 该审查涵盖了包括胃癌,卵巢癌,结直肠癌,恶性腹膜间皮质瘤和伪腹膜瘤在内的原发性恶性瘤.
- 检查了适应症的进展,目标患者群体和危险因素.
结论:
- CRS和HIPEC代表了围表面恶性瘤的新兴治疗方式.
- 进一步的研究和仔细的患者选择对于优化结果至关重要.
- 本综述确定了这种治疗方法的关键方面.
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