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Updated: Jun 24, 2025

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GNAS突变通过激活MEG3在生长激素分泌的垂体腺瘤中抑制细胞入侵

Chao Tang1, Chunyu Zhong2, Junhao Zhu1

  • 1Department of Neurosurgery, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China.

Oncology research
|June 3, 2024
PubMed
概括

具有GNAS突变的生长激素分泌的垂体腺瘤显示出侵袭性降低. 这与MEG3表达的增加有关,这抑制了通过Wnt/β-catenin通路的瘤细胞入侵.

关键词:
在EMT中,EMT是EMT.在 GHPA 中,GHPA 是高度平衡.在GNAS中发生突变.在MEG3中,MEG3是MEG3,MEG3是MEG3.这是一种β-catenin.

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