诊断工作和当前的传染性内心炎的治疗策略在儿科患者群体
Yasin Essa1, Sameh M Said1,2
1Department of Surgery, Division of Pediatric and Adult Congenital Cardiac Surgery, Maria Fareri Children's Hospital, Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595 USA.
概括
由于先天性心脏病和医疗干预,儿童感染性内心炎 (IE) 正在增加. 目前关于治疗儿科IE的指导方针缺乏证据,因此需要对这种独特人群进行审查.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 传染性疾病 传染性疾病
- 心血管外科心血管外科
背景情况:
- 传染性内心炎 (IE) 在儿科患者群体中是一个重大挑战,其发病率和严重后果日益增加.
- 患有先天性心脏病 (CHD) 的儿童的生存率提高,心脏内置假肢的使用增加以及与导管相关的干预措施有助于IE率的上升.
- 目前对儿科IE的管理指南在很大程度上是从成年人的数据中推断出来的,显着缺乏针对儿童的具体基于证据的建议.
研究的目的:
- 审查儿科人口中传染性内心炎的流行病学,临床表现,微生物学和结果.
- 分析导致儿童发生IE的病因和诱导因素.
- 讨论和评估针对儿科IE病例量身定制的不同治疗策略.
主要方法:
- 这项研究是对儿童感染性内心炎现有文献的叙述性综述.
- 该审查综合了有关儿科IE原因,风险因素和管理方法的信息.
- 分析了来自各种来源的数据,以提供全面的概述.
主要成果:
- 儿童中IE的发病率正在增加,这与心脏病治疗和医疗器械使用的进步有关.
- 在管理儿科IE方面存在特殊挑战,包括改变抗生素预防指南的影响.
- 对于专门针对儿科患者的基于证据的指导方针,有极大需要.
结论:
- 由于独特的流行病学和临床因素,儿童感染性内心炎需要专门的理解.
- 进一步的研究是必不可少的,以开发最佳的,基于证据的儿童IE的管理策略.
- 考虑病因,易感因素和量身定制的治疗方法的综合方法对于改善IE儿童的治疗结果至关重要.
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