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与COVID-19疫苗相关的淋巴腺病:一篇综述

Valeria Ciliberti¹, Elisabetta Maffei¹, Valentina Giudice²

¹UOC di Anatomia Patologica, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Italy.

Le infezioni in medicina

|June 3, 2024

概括

与COVID-19疫苗相关的淋巴腺病变 (C19-LAP) 和在成像检测到的亚临床淋巴腺病变 (SLDI) 是常见的. 活检显示这些通常是反应性的,而不是癌症,有助于在瘤患者的诊断.

科学领域:

病理学病理学病理学
在瘤学瘤学.
免疫学免疫学免疫学

背景情况:

COVID-19疫苗可以导致淋巴腺病变 (C19-LAP).
在成像检测下检测到的亚临床淋巴腺病变 (SLDI) 通常是癌症查中的偶然发现.
区分这些疾病与恶性瘤至关重要,特别是在瘤学患者中.

研究的目的:

审查SLDI和C19-LAP的临床,组织学和细胞学特征.
调查SLDI和C19-LAP的各种工具的诊断实用性.
为了澄清COVID-19疫苗接种和偶然成像发现后的淋巴腺病的性质.

主要方法:

在PubMed和Google Scholar上进行了系统的文献搜索,寻找C19-LAP和SLDI组织病理学/细胞病理学方面的研究.
获取了31份报告,并纳入了综合分析.
分析了54名患者的临床,组织学和细胞学数据.

主要成果:

大多数SLDI和C19-LAP病例是良性病例,包括反应性淋巴腺病症 (28),毛囊过度增生 (13),以及其他非恶性病症.
只有两个病例被诊断为转移,一个是具有异常毛囊的反应性增生症.
使用了诸如手术切除,核心针活检 (CNB) 和细针吸收细胞学 (FNAC) 等诊断工具.

结论:

SLDI和C19-LAP主要是反应性疾病,很少代表恶性病变.
这些发现可能会构成诊断挑战,特别是在瘤患者中.
了解C19-LAP和SLDI的特点有助于准确的诊断和患者管理.

关键词:

在这里,我们可以看到COVID COVID COVID.细胞科学细胞学组织学组织学组织学淋巴腺病变 - 淋巴腺病变疫苗疫苗疫苗疫苗

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