PAHPhysRAD:医学研究中的数字成像和通信工具,用于细分和放射性特征提取
Daniel Arrington1, Ryan Motley1, Zachery Morton Colbert1
1Department of Radiation Oncology, Cancer Services, Princess Alexandra Hospital, Woolloongabba, Australia.
Journal of medical physics
|June 3, 2024
概括
PAHPhysRAD软件自动对有风险的器官和瘤体积进行细分,提取放射性和剂量体积特征用于放射治疗. 验证证实了它与既有工具的准确性,增强了医疗图像分析.
科学领域:
- 医疗成像医学成像
- 辐射疗法 辐射疗法
- 计算生物学 计算生物学
背景情况:
- 对有风险的器官 (OAR) 和瘤体积的准确细分对于放射治疗的规划和预测结果至关重要.
- 现有的工具可能需要大量的手动输入或缺乏全面的特征提取能力.
研究的目的:
- 开发PAHPhysRAD,用于半自动化和全自动化OAR细分的研究工具.
- 为了从瘤体积中提取放射性特征和剂量体积参数.
主要方法:
- PAHPhysRAD是用 MATLAB 开发的,包括手动,半自动 (使用 Segment Anything Model) 和自动分割选项.
- 放射性特征提取与3D SlicerTM使用非小细胞肺癌患者数据进行了验证.
- 用乳腺癌治疗计划数据,对Eclipse进行了剂量-体积参数提取的验证.
主要成果:
- 通过PAHPhysRAD和3D SlicerTM提取的放射性特征之间没有发现显著差异.
- 通过PAHPhysRAD计算的平均肺和心脏剂量与Eclipse的剂量非常接近,差异很小.
结论:
- PAHPhysRAD为医疗图像分析提供了一个用户友好的基于 MATLAB 的平台.
- 该软件有助于高效细分和提取放射性和剂量体积参数,这对于研究来说非常有价值.
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