相关实验视频
Updated: Jun 24, 2025
09:09
Gene Expression Analyses in Human Follicles
Published on: February 17, 2023
1.1K
复合人卵泡刺激激素在中国辅助生殖技术的受控卵巢过度刺激中:成本效益分析
Hongchao Li1, Wei He2, Hongbo Lin3
1School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, 211198, People's Republic of China.
Risk management and healthcare policy
|June 3, 2024
概括
在中国的辅助生殖技术患者中,原始人复合人卵泡刺激激素α (rhFSH-α) 与其生物类似物相比,显示出较高的累积活产率和较低的活产成本.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 药物经济学 药物经济学
- 生物技术是生物技术.
背景情况:
- 在辅助生殖技术 (ART) 中评估复合人卵泡刺激激素α (rhFSH-α) 治疗的成本效益.
- 从中国患者的角度比较原始物 (follitropin alfa,GONAL-f) 和生物类似物 (rhFSH,JinSaiHeng).
研究的目的:
- 评估GONAL-f与JinSaiHeng在ART中的成本效益.
- 确定中国不育妇女的rhFSH-α治疗的经济价值.
主要方法:
- 开发了一个决策树模型来模拟ART治疗途径.
- 利用已发表的临床和成本数据进行rhFSH-α评估.
- 估计的累积活产率 (CLBR),直接医疗费用和每 CLBR 的成本.
主要成果:
- GONAL-f获得的CLBR (88.3%) 比JinSaiHeng (84.4%) 更高.
- 相比于JinSaiHeng (52,095 CNY),GONAL-f (51,475 CNY) 的累计活产成本较低.
结论:
- 原始体rhFSH-α (GONAL-f) 提供了更高的CLBR和更低的活产成本.
- 对于GONAL-f,每个额外的活产儿的增量成本为38,096元人民币.
更多相关视频
05:32Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
Published on: August 11, 2023
1.7K
08:46Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
5.9K
相关概念视频
01:24In Vitro Fertilization
247
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
247
01:30Hormonal Control of the Ovarian Cycle
468
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
468