含有的专业供应剂与内置的氨酸的虫预防潜力:一个范围审查
Nouf Ali Alblooshi1, Tiba Kahtan Naseer1, Mohammed Nadeem Bijle2
1Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.
The Japanese dental science review
|June 3, 2024
概括
专业应用的化物与氨酸一起显示出预防虫的潜力. 然而,目前的研究仅限于体外研究,因此需要进行临床试验,以获得关于氨酸-化物疗效的确证据.
科学领域:
- 牙科材料科学 牙科材料科学
- 牙损伤研究预防研究
- 化物和氨酸的应用.
背景情况:
- 素 (Arg) 和化物 (F) 是预防虫的关键剂.
- 调查专业可交付的含有F的药物,其中含有Arg,至关重要.
- 关于Arg-F干预措施的联合疗效的临床数据有限.
研究的目的:
- 调查含有氨酸的专业可提供化剂的虫预防潜力.
- 为了确定研究缺口和未来的方向对化干预在虫预防.
主要方法:
- 对已识别的记录进行了范围审查.
- 包含的研究重点是专业牙科药剂中氨酸变体 (L-Arg/Arg.HCl) 的体外研究.
- 在化物涂料,MI涂料/纳米氧酸和玻璃离子体水泥中氨酸结合的分析.
主要成果:
- 包括七篇文章,主要是体外研究;没有发现临床研究.
- 四项体外研究探讨了5%的L-Arg丰富NaF漆 (Duraphat®) 作为一个有前途的药物.
- 在其他化漆和牙科材料中氨酸的结合在很大程度上仍未被探索.
结论:
- 氨酸显示了将其纳入专业可交付的化物剂中,以预防空的潜力.
- 目前的证据主要来自体外研究,缺乏临床验证.
- 需要进一步的研究,特别是临床试验,以确定Arg-F干预的有效性.
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