吸烟对三级心房阻塞结果的影响:倾向匹配分析
Mirza Faris Ali Baig1, Kalyan Chaliki2
1Asante Three Rivers Medical Center, 500 SW Ramsey Avenue, Grants Pass, OR, USA, 97527.
概括
患有第三级心房 (AV) 阻塞和吸烟史的患者在医院死亡率和费用较低. 这项研究分析了5560名匹配患者,发现吸烟者有更好的结果,包括减少心脏性休克和更短的住院时间.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 第三度心房静脉 (AV) 阻塞是一种罕见但严重的需要立即干预的疾病,通常归因于冠状动脉疾病 (CAD).
- 吸烟是CAD的主要风险因素,但其对第三级AV阻塞结果的直接影响尚未得到充分证实.
研究的目的:
- 为了研究吸烟史和诊断为第三级AV阻塞的患者的临床结果之间的关联.
- 分析医院死亡率,并发症率和与吸烟状况相关的医疗保健资源利用情况.
主要方法:
- 一项回顾性队列研究利用了2019-2020年国家住院样本 (NIS) 数据库.
- 包括初步诊断为三级心血管阻塞的成年患者,以及有吸烟史的患者.
- 分析了包括死亡率,心脏性休克,心脏骤停,停留时间 (LOS) 和住院费用在内的结果,使用多变量回归和倾向得分匹配.
主要成果:
- 该研究包括77,650人入院,其中29,380 (37.8%) 患者被确定为吸烟者.
- 在倾向得分匹配后 (5,560名患者),吸烟者在住院死亡率的几率显著降低 (aOR,0.59;CI,0.44-0.78).
- 吸烟者还经历了心脏性休克,心脏骤停,气管管道输入,机械呼吸,较短的LOS和较低的住院费用的减少.
结论:
- 与非吸烟者相比,有吸烟史的第三级心血管阻塞患者在医院内表现更好.
- 这些结果包括较低的死亡率,较少的严重并发症,如心脏性休克和心脏骤停,以及减少医疗保健资源利用率.
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