21DSCAM

David M McKean1,2, Qi Zhang1, Priyanka Narayan1,3

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.

概括

三胞胎症21 (T21) 通过影响心脏细胞中的DSCAM基因表达,增加了Wnt抑制剂的硬质素. 这可能解释了唐氏综合征表型,并建议针对T21相关疾病的抗硬质素疗法.

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