外部电气和药理心脏转换用于心房动,心房动或心房高心率:一个网络元分析
Kishore Kukendrarajah1, Mahmood Ahmad2, Mafalda Carrington3
1Barts Health NHS Trust, London, UK.
The Cochrane database of systematic reviews
|June 3, 2024
概括
本综述比较了心房动 (AF) 和动的药理学和电动心脏转变. 使用特定波形的电动心脏转换和诸如素之类的药物在恢复鼻节律方面表现出高效.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 心房动 (AF) 是最常见的持续性心律失常.
- 使用药物或电击的心转术旨在恢复正常的鼻节律.
研究的目的:
- 评估药物和电动心脏转换的疗效和安全性.
- 为了比较心脏动 (AF),心脏动和心脏动的治疗方法.
主要方法:
- 进行了112项随机对照试验 (RCT) 的网络元分析,涉及15968名患者.
- 搜索了多个数据库 (CENTRAL,MEDLINE,Embase) 至2023年2月.
- 使用GRADE评估证据质量,并使用频率主义方法进行数据分析.
主要成果:
- 在 Paroxysmal AF 中,电动心脏转变 (AA/AP BTE) 和药物 (金尼丁,伊布蒂利德,普罗法芬,阿米奥达龙,索塔醇,普罗卡因胺) 显著增加了鼻节律的维持.
- 对于持久性AF,特定的电心转变策略 (AP BTE最大能量,主动压缩) 显示出高效.
- 对于心房,抗心律失常药物 (伊布立德,普罗帕芬,多费提利德,索塔醇) 显示出高效;电动心脏转换几乎100%有效.
结论:
- 这篇综述提供了对AF和心房的电气和药理心脏转变策略的关键见解,尽管证据质量有限.
- 患者的并发症,药物概况和需要镇静/麻醉的需要是选择最佳心脏转换方法的关键因素.
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