慢性鼻炎与鼻的结果措施
A R Sedaghat1, R G Campbell2,3,4, R G Douglas5
1Department of Otolaryngology Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Rhinology
|June 3, 2024
概括
长期鼻炎与鼻息肉 (CRSwNP) 的新疗法需要强有力的结果测量. 本综述详细介绍了患者报告的结果措施 (PROM),客观测试,心理物理测试和评估CRSwNP的生物标志物.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床试验 临床试验
- 医学诊断 医学诊断 医学诊断
背景情况:
- 慢性鼻炎与鼻息肉 (CRSwNP) 的新疗法需要全面的结果测量.
- 现有的措施包括患者报告的生命质量和症状严重性的结果措施 (PROMs).
- 客观测试,心理物理测试和生物标志物也对于评估CRSwNP至关重要.
研究的目的:
- 审查和描述CRSwNP的各种结果措施.
- 为了评估CRSwNP治疗的疗效.
- 提供可用的评估工具的全面概述.
主要方法:
- 进行了叙事文学评论.
- 确定和描述了CRSwNP评估和治疗响应评估的结果措施.
- 检查了每个措施的历史,验证,心理测量性能和局限性.
主要成果:
- 确定了CRSwNP的多种结果指标,分为PROM,客观测试,心理物理测试或生物标志物.
- 审查详细介绍了每项措施的历史发展和开端研究.
- 介绍了正式验证,心理测量表现以及每个结果测量的局限性.
结论:
- PROM,客观测试,心理物理测试和生物标志物是CRSwNP的补充措施.
- 这些不同的结果措施有助于评估CRSwNP疾病状况和治疗疗效.
- 了解每个措施的验证,性能和局限性对于准确的解释至关重要.
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