印度青少年2型糖尿病发展过程的决定因素
Dhvani Raithatha1, Proteek Sen1, Chetankumar Dave1
1Department of Pediatric Endocrinology, Regency Center for Diabetes Endocrinology & Research, Regency City Clinic, Opposite PPN Market, Kanpur, 208001, India.
Indian journal of pediatrics
|June 3, 2024
概括
印度青少年的2型糖尿病往往是晚期出现的,并且进展迅速. 通过查进行早期诊断和实现缓解是管理这种疾病更好的结果的关键因素.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 公共卫生 公共卫生
背景情况:
- 全球范围内,2型糖尿病 (T2D) 在青少年中越来越多地被诊断为糖尿病.
- 印度青少年代表了一个独特的人口统计学,具有特定的风险因素和疾病轨迹.
- 了解这一群体T2D进展的决定因素对于有效的管理至关重要.
研究的目的:
- 确定影响印度青少年2型糖尿病临床过程的因素.
- 分析这个队列中的治疗模式和结果.
- 确定疾病进展和缓解的预测因素.
主要方法:
- 对37名被诊断患有T2D的印度青少年的医疗记录进行了回顾性审查.
- 收集的数据包括初始诊断参数 (HbA1C,BMI SDS),家族病史和治疗方案.
- 随访数据分析了疾病进展,缓解率和需要联合治疗的情况.
主要成果:
- 青少年在平均年龄为15.2岁时被诊断出高初始HbA1C (10.1%) 和BMI SDS (2.0).
- 近30%的患者得到了缓解,但超过一半的患者在两年内复发.
- 在随访期间,对多种抗糖尿病药物的需求显著增加.
结论:
- 印度青少年的2型糖尿病的特点是延迟呈现和快速进展.
- 早期诊断的查和实现缓解是有利疾病进程的重要预测因素.
- 经常需要加强治疗,这突显了T2D在这个人群中的侵略性.
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