[炎症性关节疾病的男性阴性腺症:频率和临床特征]
T S Panevin1,2, R V Rozhivanov3, E G Zotkin1
1Nasonova Research Institute of Rheumatology.
Terapevticheskii arkhiv
|June 3, 2024
概括
阴高性腺症 (HG) 影响17-32%的男性患有类风湿性关节炎,化脊柱炎和牛皮性关节炎. 虽然与疾病阶段无关,但HG与这些类风湿性疾病中炎症和代谢问题增加有关.
科学领域:
- 风湿病学和内分泌学.
- 男人的健康 男人的健康
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 类风湿性关节炎 (RA),性脊柱炎 (AS) 和牛皮性关节炎 (PsA) 是慢性炎症性疾病.
- 低激素 (TS) 水平的特征是低激素 (HG) 低激素 (TS) 水平的特征,是男性患有类风湿性疾病 (RDs) 的潜在并发症.
研究的目的:
- 在被诊断为RA,AS和PsA的男性中确定HG的频率.
- 调查HG对这些类风湿性疾病和相关并发症的临床表现和病程的影响.
主要方法:
- 一项涉及170名RA患者,57名AS患者和85名PsA患者的研究.
- 评估总 (TS) 水平以确定HG,然后对具有和没有HG的患者之间的临床,人口和实验室标记进行比较分析.
主要成果:
- 在RA中,TS缺陷 (HG) 的发生率为24.1%,在AS中为17.5%,在PsA中为31.8%.
- 在RA中HG与更高的BMI,葡萄糖,尿酸,ESR和贫血有关. 在AS中,HG与较低的血红蛋白,贫血,较高的CRP和ESR相关. 在PsA中,HG与年龄较大,BMI较高,葡萄糖和肥胖有关.
- 尽管存在这些关联,但HG与RD的阶段或活性无关,HG患者群体的激素水平和疾病标志物在特定的RD中都相似.
结论:
- 低水平和HG在RA,AS和PSA的男性中很常见.
- 高血压与炎症标志物增加,贫血和代谢障碍有关,但不是疾病阶段或活动.
- 无论其具体的类风湿性疾病如何,HG患者表现出相似的性激素配置文件和与疾病相关的指标.
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