动态观察和深静脉血栓形成的危险因素分析骨折后的骨折
Yuxuan Cong1, Baohui Wang2, Chen Fei3
1TCM Rehabilitation Department, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of China.
PloS one
|June 3, 2024
概括
骨折后的深静脉血栓 (DVT) 主要发生在前三天内,在第一天达到顶峰. 低血位 (<40%) 是严重的DVT发展的独立风险因素.
科学领域:
- 整形外科手术 整形外科手术
- 血管医学 血管医学
- 血栓形成研究研究
背景情况:
- 骨折与深静脉血栓形成 (DVT) 的高风险有关.
- 了解DVT骨折后骨折的动态性质和风险因素对于及时干预至关重要.
- 以前的研究还没有完全阐明这个患者群体内DVT的时间模式和特定风险因素.
研究的目的:
- 动态观察骨折后深静脉血栓症 (DVT) 的发生率.
- 识别和分析影响骨骨折后DVT的动态发生和变化的风险因素.
主要方法:
- 从2017年1月到2021年8月,对331名关节骨折患者进行了回顾性分析.
- 每天采用多普勒超声波,将患者分为DVT和非DVT组.
- 生存分析,日志等级测试和Cox比例危险回归以评估随时间推移的DVT发生情况并确定风险因素.
主要成果:
- 44.7%的患者在手术前出现了DVT,其中96.6%的患者在入院后的前三天内出现了DVT.
- 在第一天 (42%) 观察到最高的DVT发病率,在一周内稳定.
- 严重内脏病的独立风险因素包括年龄>70,胸腔间骨折,低摄入血红蛋白 (<130g/L) 和低摄入血红素 (<40%).
结论:
- 骨折后的深静脉血栓主要在最初的三天内表现出来,在第一天发生的高峰发病率.
- 年龄,骨折类型,血红蛋白和血红素水平显著影响DVT的动态发生.
- 血红素水平低于40%被确定为一个独立的危险因素,增加了2,079倍的DVT风险.
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