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Updated: Jun 24, 2025

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在类风湿性关节炎纤维细胞样同胞细胞中对homeobox D10表达的联合特异性调节

Hyeonjeong Lee1, Camilla R L Machado1, Deepa Hammaker1

  • 1Division of Rheumatology, Allergy and Immunology, School of Medicine, University of California San Diego, La Jolla, California, United States of America.

PloS one
|June 3, 2024
PubMed
概括

风湿性关节炎 (RA) 纤维细胞样同胞细胞 (FLS) 的表观遗传差异影响关节特异性HOXD10表达. 基因组脱乙酶1 (HDAC1) 抑制使这些模式正常化,这表明RA关节参与的治疗标.

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